News

Congrats to Tatyana Dobreva, David Brown , Jeff Park and Matt Thomson for their paper on single-cell profiling of capillary blood!

Fresh off the press at Scientific Reports!  https://www.nature.com/articles/s41598-020-77073-3

What’s cool about this paper: capillary blood sampling devices (TAP devices) allowed the team to collect blood at high temporal frequencies (morning and nigh). They used this system to study diurnal variability in a cell type-specific and patient-specific manner.

News

Single-cell Superusers Meeting: Dr. Colt Egelston and Dr. Weihua Guo (City of Hope)

Dr. Colt Egelston and Dr. Weihua Guo (City of Hope) present at the single-cell superusers meeting about immuno-oncology, breast cancer, and signatures of T cell exhaustion.
Talk title: Utilization of single-cell transcriptomics to interrogate immune cell composition in clinical tumor samples
Abstract:
Single-cell RNA sequencing technologies offer unique and powerful solutions towards greater understanding of cellular biology. Here we will discuss implementation of a successful single-cell RNA sequencing analysis pipeline for evaluation of clinical patient samples. We will discuss recent advances in understanding composition and function of tumor infiltrating lymphocytes from clinical patient samples at the City of Hope using our current approaches. Finally, we will discuss harnessing single-cell transcriptomic derived data towards evaluating responders in immunotherapy-based clinical trials and designing new immunotherapy approaches via advanced computational approaches.