Congrats to David and Tatyana for publishing their paper on profiling AAV tropism with single-cell RNA-seq

Paper can be found at:

What’s cool about this paper: They developed a single-cell RNA sequencing (scRNA-seq) pipeline for in vivo characterization of barcoded rAAV pools at high resolution. They were able to faithfully identify cell-type specific tropisms in a pool of up to 7 variants simultaneously, paving the way for future highly multiplexed screens.